Author

Kokichi Hashimoto

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Aug 2026

Deep Learning Versus LASSO-Based Machine Learning for 1-Year Survival After Surgery for Spinal Metastases: A JASA Multicenter Prospective Cohort Analysis.

STUDY DESIGN Multicenter prospective cohort study; secondary analysis. OBJECTIVE To evaluate predictors associated with 1-year survival after surgery for spinal metastases by comparing a comprehensive 50-variable deep learning (DL) model with a previously published 5-variable LASSO-based machine learning (ML) model a...

S. Ito, Hiroaki Nakashima, N. Segi et al. · Spine · 0 citations

Open access Sep 2026

MA-5 attenuates disease-associated transcriptomic aging and pathological microglial states in Gaucher disease

Overall, MA-5 suppresses neuroinflammation and reverses accelerated transcriptomic aging, supporting its potential as a therapeutic strategy for GD and other lysosomal storage disorders, as well as for diseases characterized by mitochondrial dysfunction, chronic inflammation, and pathological accumulation.

Y. Tongu, Tomoko Kasahara, Kohta Nakamura et al. · Research Square · 0 citations