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Author

Kong-Peng Lam

2 papers indexed here

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Review Open access Sep 2026

IL-10’s contextual role in cytotoxic antitumor immunity: evidence, controversies, and therapeutic translation

Interleukin-10 (IL-10) is classically defined as a potent anti-inflammatory cytokine that protects tissues by constraining myeloid activation and limiting inflammatory cytokine production. Yet, accumulating evidence indicates that, in defined contexts, IL-10 can also promote antitumor immunity by enhancing the fitness...

Min-Chuan Zhang, Qi-Jing Li, Kong-Peng Lam et al. · 0 citations
Open access Jul 2026

G3BP1 methylation by PRMT5 facilitates its recruitment of TBK1 for IRF3 activation during host response to foreign ribonucleic acids

The study reveals a role for G3BP1 in binding TBK1 and IRF3, two important molecules in innate immune signaling leading to the production of IFN-β and indicates that G3BP1 could bind PRMT5, TBK1 and IRF3 and reveal G3BP1 as a signaling hub that constitutively binds IRF3.

Wen Song, Susana Soo-Yeon Kim, C. Yam et al. · 0 citations

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