Chlamydia muridarum TC0066 is required for invasion and intracellular development in tissue culture but dispensable in the murine infection model
Results indicate that TC0066 and C. trachomatis TmeA exhibit conserved functions, but these activities do not translate to detectable, overt changes to in vivo genital-tract pathogenesis, emphasizing the need for care when interpreting outcomes of human chlamydial infection in the murine model.