Open access
Aug 2026
Genome folding and nuclear speckles converge to orchestrate fibroblast activation
The role of the critical nuclear speckle component SON was examined and it was shown that it is required for myofibroblast gene expression and support a model in which distinct facets of genome organization converge to orchestrate cell-state transitions.
Zachary Gardner, Ricardo Linares-Saldana, Krishna Kumar Haridhasapavalan et al.
· Science Advances · 0 citations