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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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Kristýna Čunátová

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Open access Aug 2026

Polyunsaturated fatty acid sequestration protects against mitochondrial dysfunction-induced ferroptosis

Impaired energy production is a hallmark of mitochondrial oxidative phosphorylation (OXPHOS) defects. However, secondary metabolic disturbances also represent an important trigger for pathologies originating from OXPHOS aberrations. Here we show that cells with OXPHOS deficiencies accumulate triacylglycerols enriched i...

G. Puertas-Frías, María José Saucedo-Rodríguez, Kristýna Čunátová et al. · 0 citations

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