Open access
Jul 2026
Single-cell RNA-seq and spatial transcriptomics characterize CD8+ exhausted T cells in pancreatic ductal adenocarcinoma
Low SPP1 and PLAUR expression correlated with poor prognosis in TCGA-PAAD and two key LR pairs mediated crosstalk between cancer cells and CD8+ Tex cells, confirmed by immunofluorescence, spatial mapping, and protein docking.
Jing Mao, Chenxin Yan, Ying Mei et al.
· iScience · 0 citations