Author

Kumaraswamy Gandla

3 papers indexed here

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Open access Oct 2026

Isolation structural characterization and molecular docking analysis of bioactive phytoconstituents from Hiptage madablota Gaertn root as human pancreatic lipase inhibitors

This study explores the phytochemical profile and computationally predicted interaction potential with human pancreatic lipase of the ethanol extract of Hiptage madablota Gaertn., a plant of ethnopharmacological relevance. High-performance thin-layer chromatography (HPTLC) analysis revealed the presence of six distinct...

G. Retnasamy, S. Adikay, A. Saravanakumar et al. · Discover Chemistry · 0 citations

Open access Sep 2026

Quality by design-assisted development of an intranasal Shikonin-loaded Mucoadhesive microemulsion for enhanced brain delivery: optimization, characterization, and Pharmacodynamic evaluation in a schizophrenia model.

The present study aimed to develop and optimize a shikonin-loaded mucoadhesive microemulsion for intranasal delivery with the objective of improving nasal residence and facilitating central drug delivery. Shikonin is a naturally occurring naphthoquinone derivative with reported anti-inflammatory and neuroprotective pro...

Pavan Kumar Inuganti, K. Gandla, Lalitha Repudi et al. · Bioorganic chemistry (Print) · 0 citations

Review Open access Sep 2026

From Targeted LC-MS/MS to High-Resolution Mass Spectrometry: Emerging Analytical Strategies for the Characterization of Antiviral and Antibacterial Drugs, Impurities and Degradation Products: A Critical Review

Overall, the available evidence supports an integrated analytical strategy in which HRMS is primarily employed to elucidate chemical identity and targeted LC-MS/MS is applied when sensitive, selective and robust routine quantification is required.

Niloufer Tasnim Khazi, K. Gandla · Pharmacology & toxicology re... · 0 citations