Author

Kun Li

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Review Open access Sep 2026

Multi-kingdom microbial diversity and interaction landscapes in mosquitoes revealed by 5,163 individual meta-transcriptomes

This study conducted a nationwide single-mosquito meta-transcriptomic survey of 5,163 mosquitoes representing 100 species across China, integrating viral discovery with marker-gene profiling of bacteria, archaea, fungi, and other eukaryotic microbes to establish a detailed view of the full-spectrum microbiome.

Qin-yu Gou, Wei-Chen Wu, Pei-Bo Shi et al. · bioRxiv · 0 citations

Open access Aug 2026

Virus-induced deconjugation of ISG15 dysregulates innate immunity and cellular metabolism.

Genetically ablated the deISGylating activity of the SARS-CoV-2-encoded papain-like protease (PLpro) and found that loss of deISGylation boosted innate immune activation, attenuated viral replication, and promoted viral clearance in human cells and mice.

Jun-Ji Zhu, Guan-Qun Liu, Jie-Lin Xu et al. · Immunity · 1 citation