Author

Kun-Shuang Shen

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Review Open access Aug 2026

Breast cancer-related fatigue: Mechanisms, biomarkers, risk factors, and intervention strategies

Breast cancer-related fatigue (BCRF) is a prevalent and debilitating condition that affects patients during and after treatment. It is characterized by persistent, distressing physical and psychological exhaustion that is disproportionate to recent activity and unrelieved by rest. This review synthesizes current eviden...

Chao Zhao, Qi Qiu, Yuan-Yuan Wang et al. · Breast · 0 citations

Open access Sep 2026

Integrated Systems Toxicology Analysis and Molecular Dynamics Study Reveal the Potential Mechanism by which Benzo[a]pyrene Contributes to Depression in Lung Adenocarcinoma via RNASE1 Upregulation

Docking and MD analyses supported stable Bap–RNASE1 binding, involving hydrophobic interactions with key residues and a dominant low-energy conformational state, which provides molecular-level mechanistic insight into the cancer–depression comorbidity driven by environmental carcinogens.

Jing-Zhe Gao, Fu-Xiang Huang, Kun-Shuang Shen et al. · ACS Omega · 0 citations