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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Kun Zhang

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2 papers indexed here

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Jul 2026

Reticulocalbin‐2–Programmed Macrophage Exosomes Restore Immuno‐Osteogenic Coupling to Promote Calvarial Bone Regeneration

Calvarial defect repair is frequently limited by immune dysregulation and insufficient coupling with bone regeneration. This study investigated the regulatory role of reticulocalbin‐2 (RCN2) in macrophages and evaluated a biomimetic periosteum‐bone bilayer scaffold (PB‐BLS) designed to deliver RCN2‐modified M2 macropha...

Jiajia Lu, Sheng Zhou, Long Yang et al. · 1 citation
Jul 2026

Flavin adenine dinucleotide is an endogenous suppressor for cytosolic DNA and RNA sensors to modulate innate immunity.

Cytosolic DNA and RNA sensing is crucial for innate immunity, playing essential roles in pathogen defense and autoinflammation induction. We reported the endogenous metabolite flavin adenine dinucleotide (FAD) as a molecular brake restraining both cytosolic DNA and RNA sensing. It bound directly to cytosolic nucleic ac...

Yao Wang, Yanyan Shen, Jiayu Liu et al. · 0 citations

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