Open access
Aug 2026
A massively parallel CRISPR-based screening platform for modifiers of neuronal depolarization
A platform to uncover genes affecting neuronal excitability in scalable CRISPR screens using CRISPRi and the fluorescent calcium integrator CaMPARI2 is developed to uncover molecular mechanisms controlling neuronal function in health and disease.
Steven C. Boggess, Vaidehi Gandhi, Ming-Chi Tsai et al.
· Nature Communications · 0 citations