Kunhua Dong

THGAgents: Traceable Biomedical Hypothesis Generation via Dynamic Causal Reasoning

THGAgents utilizes collaborative and dynamically updating agents to build a Traceable Causal Knowledge Graph, which serves as the foundation for the evidence-based knowledge structure and employs an LLM-driven heuristic search algorithm to traverse the complex network, balancing both novelty and rigor to deduce strict, evidence-based mechanistic causal chains.