Tumor microenvironment-activatable, glucose oxidase-templated nanocatalyst for self-reinforcing starvation and chemodynamic cancer therapy.
Glucose oxidase (GOx)-based starvation therapy (ST) is limited by tumor hypoxia, restricted substrate availability, and inefficient enzyme utilization in carrier-based systems. Here, we developed a tumor microenvironment-responsive GOx-templated MnO2/Co2+ (GMC) nanocatalyst for synergistic ST and chemodynamic therapy (...