Apoptosis plays an important role in sepsis-associated immune dysfunction, particularly through lymphocyte depletion and the development of persistent immunosuppression. This review examines apoptosis-associated biomarkers in sepsis, distinguishing relatively direct markers of cell death from complementary indicators o...
O. Coman, L. Azamfirei, Oana Frandeș et al.· Biosensors· 0 citations
Background: Nutritional support in critically ill patients remains one of the most debated aspects of intensive care medicine. Although international guidelines have long recommended early nutritional support with progressive protein delivery, recent clinical evidence has questioned the benefit of aggressive early calo...
M. Stoian, A. Stoian, C. Bănescu et al.· Nutrients· 0 citations
Background/Objectives: Healthcare digital twins are being developed at scales ranging from individual organs to regional health systems. However, the literature at these different scales has largely evolved independently. This narrative review examines how the concept changes as the represented object grows, and propos...
L. Azamfirei, D. Bica, Andrei Calin Dragomir et al.· Healthcare· 0 citations
AI has considerable potential to support AMR prediction and antimicrobial stewardship, but broader implementation will require rigorous validation, integration into clinical workflows, continuous monitoring and demonstration of clinical benefit.
Oana Frandeș, L. Azamfirei, Oana-Elena Branea et al.· Medicina· 0 citations
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