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L. B. de Arruda

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Open access Sep 2026

Type I IFN coordinates resistance and tolerance against Zika virus disease by inducing NK cell recruitment and limiting neutrophil-driven neuropathology in the brain

Zika virus (ZIKV) neurological disease arises from both direct viral cytopathic effects in the central nervous system (CNS) and host-driven neuroinflammation, with disease outcomes determined by the balance between antiviral resistance and disease tolerance. Type I interferons (IFN-I) are well-established antiviral med...

Luan Rocha Lima, S. V. A. Coelho, L. M. Meuren et al. · 0 citations

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