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Open access Aug 2026

A functional missense variant in MRI1 links methionine salvage to reduced type 2 diabetes risk

Summary Type 2 diabetes (T2D) pathogenesis is shaped by both risk and protective genetic variants, but mechanisms underlying disease protection remain understudied. Previously, in a population isolate with high T2D prevalence, we unexpectedly identified a relatively frequent protective missense variant (Arg149Cys, rs55...

Khushdeep Bandesh, M. Traurig, Kendrick Freeland et al. · 0 citations

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