Open access
Sep 2026
P2X4 Receptor Antagonists Exert Anti-Inflammatory Effects via NLRP3 Inflammasome in a Murine Model of Colitis
Pharmacological inhibition of P2X4 receptors (P2X4Rs) has emerged as a potential therapeutic approach for the management of several immune/inflammatory diseases. However, the contribution of P2X4Rs in the pathophysiological mechanisms underlying colitis-associated intestinal inflammation remain partially unclear. Her...
V. D'Antongiovanni, C. Di Salvo, M. Fornai et al.
· ACS Pharmacology & Trans... · 0 citations