Open access
Sep 2026
Tph2 deficiency shapes neurodevelopmental behavioral trajectories through interactions with the maternal environment, sex, and the gut microbiome
It is demonstrated that 5-HT depletion disrupts behavioral neurodevelopmental trajectories via interactions between genetic, environmental, and ecological factors, highlighting the importance of accounting for sex, environment, and developmental timing in translational research.
Marta C. F. Samina, Rogério C. R. Castro, Thijs Lodder et al.
· Translational Psychiatry · 0 citations