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Open access Sep 2026

BMP4 and FGF2 promote heterogeneous priming including extraembryonic lineages in porcine expanded potential stem cells

Introduction Extraembryonic lineages, specifically the trophectoderm (TE) and primitive endoderm (PrE), are indispensable for early embryogenesis and successful pregnancy. Expanded potential stem cells (EPSCs) can contribute to both embryonic and extraembryonic fates, providing a platform to model early lineage specifi...

Haneul Kim, L. Cai, Sang-Hwan Hyun et al. · 0 citations

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