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Open access Sep 2026

mRNA-1273 SARS-CoV-2 vaccination in people with HIV: an immune correlates analysis of CD4 + T cell responses in the multicenter CoVPN 3008 observational study

T cell correlates of COVID-19 risk are poorly defined, particularly in people with HIV (PWH). CoVPN 3008 (NCT05168813) Part A was a prospective 14,002-participant cohort study that administered one or two doses of mRNA-1273 COVID-19 vaccine, depending on baseline SARS-CoV-2 serostatus, in participants (83% PWH) in sub-...

Sharon Khuzwayo, Bo Zhang, Valentin Voillet et al. · 1 citation
Open access Oct 2026

Correlates of Protection and Response Durability of the RTS,S Vaccine in Four Malaria Challenge Studies

RTS,S/AS01 (RTS,S) is one of two WHO-recommended malaria vaccines for children in moderate-to-high transmission settings. Yet, no validated immune correlate of protection (CoP) has been established for this vaccine. We selected 16 biomarkers to further assess as candidate CoPs, based largely on their ability to well-pr...

S.-Y. Kim, T. Linnekin, L. Carpp et al. · 0 citations

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