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L. Casettari

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Open access Aug 2026

Nanoparticles-mediated dual drug administration boosts therapeutic efficacy in drug resistant melanoma.

A dual-drug delivery system co-loading trametinib, MEK inhibitor, and alisertib, Aurora A kinase inhibitor was developed, optimized to maintain a previously established synergistic ratio which effectively overcome acquired resistance to standard-of-care therapies and induce durable tumor regression.

Giulia Lovati, Pietro Milesi, Paolo Fossati et al. · 0 citations

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