Open access
Oct 2026
Locus coeruleus intensity as a marker of early-stage Alzheimers disease: associations with plasma pTau217 and memory
INTRODUCTION: The locus coeruleus (LC) is one of the earliest sites of Alzheimers disease (AD) pathophysiological changes. LC magnetic resonance imaging (MRI) intensity may reflect effects of AD pathophysiology on the LC, providing a biomarker of early-stage AD. This study examined relationships among MRI-derived LC in...
M. Quiring, Y. Shuai, W. Zhao et al.
· medRxiv · 0 citations