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Author

L. Cupelli

2 papers indexed here

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Open access Aug 2026

Efficacy and Potential Limitation of the Menin Inhibitor Revumenib Outside Clinical Trials: Extramedullary Response with Central Nervous System Escape in a Case of KMT2A-Rearranged Acute Myeloid Leukemia

Acute myeloid leukemia (AML) harboring KMT2A rearrangements (KMT2A-r) accounts for approximately 5–10% of newly diagnosed cases and represents a high-risk AML subtype associated with poor clinical outcomes despite intensive treatment strategies, including allogeneic hematopoietic stem cell transplantation (HSCT). KMT2A...

Martina Canichella, C. Papayannidis, Mariagiovanna Cefalo et al. · 0 citations
Review Open access Sep 2026

Beyond CAR-T: Preventing and Treating Relapse in B-Cell Haematological Malignancies

Current evidence remains largely preliminary and is limited by the paucity of randomized prospective trials, although relapse management is disease-specific and increasingly incorporates novel therapeutic agents, including bispecific antibodies (BsAbs) and other targeted therapies.

Martina Canichella, E. Abruzzese, Mariagiovanna Cefalo et al. · 0 citations

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