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L. D. de Assis

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Open access Sep 2026

nnOPN3 mediates retinal-dependent lipofuscin accumulation and its loss sensitizes keratinocytes to blue-light-induced proteomic remodeling

Lipofuscin is a blue-light-absorbing pigment that contributes to oxidative damage. Whether all-trans retinal (atRAL) contributes to its formation in response to light remains unclear. We asked whether blue-light photosensitization of atRAL promotes lipofuscin accumulation in human keratinocytes and whether this depends...

Maiza Cristina Von Dentz, H. C. Junqueira, Manuel Alejandro Herrera López et al. · 0 citations

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