L. E. Dietrich

Phenazine Biosynthesis Inhibitors as Pseudomonas aeruginosa Antivirulence Agents

Phenazines are redox-active secondary metabolites produced by a variety of bacteria, including Pseudomonas aeruginosa, a Gram-negative opportunistic pathogen associated with severe, often chronic infections and particularly notorious for its multiple resistance mechanisms. A major contributor to P. aeruginosa virulen...