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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

L. Ellisen

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Open access Oct 2026

Antibody-drug conjugates in breast cancer: redefining targeted therapy

Antibody-drug conjugates (ADCs) have transformed the treatment landscape of breast cancer and redefined the conceptual distinction between targeted therapy and conventional chemotherapy. Originally conceived as “magic bullets” that selectively deliver cytotoxic warheads to antigen-expressing tumor cells, clinical and m...

Chen-Xu Guo, L. Ellisen · 0 citations
Open access Sep 2026

Actionable genetic landscape and dynamics in circulating DNA from 12,827 patients with metastatic breast cancer

Plasma cell-free DNA (cfDNA) is a sensitive, noninvasive tool for monitoring the genomic landscape, heterogeneity, and evolution of cancer, aggregating genetic information from multiple metastatic sites. Here, we study 15,564 cfDNA samples from 12,827 patients with metastatic breast cancer (MBC). We classify sample...

I. Leshchiner, A. Medford, J. Cha et al. · 0 citations

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