Sleep and wakefulness are associated with distinct cortical patterns of rhythmic activity1. During low-arousal states such as slow-wave sleep, synchronous low-frequency rhythms dominate activity across widespread cortical regions. Although inhibitory neurons are increasingly recognized as key regulators of cortical sta...
Jacob M. Ratliff, Geoffrey Terral, Arenski Vazquez et al.· Nature· 0 citations
Precise genetic access to molecularly defined neuronal subpopulations is essential for dissecting circuit heterogeneity. We developed and validated a knockin neurotensin receptor 1 (Ntsr1)Flp mouse line for intersectional targeting of Ntsr1-expressing neurons. Following delivery of Flp-dependent adeno-associated viral...
Fernando Garcia, Andrew P. Villa, Justine T. Wong et al.· Cell Reports Methods· 0 citations
A significant minority of alcohol users develop alcohol addiction, characterized by continued use despite negative consequences, referred to as compulsive-like. We previously showed that vulnerability to compulsive-like alcohol use can be modeled in rats using punished alcohol self-administration and in male rats is me...
E. Barbier, Leon Höglund, Li Xu et al.· Nature Communications· 0 citations
The results suggest that glutamate cotransmission is a distinguishing feature of VTA dopamine neuron signaling patterns and roles in natural reward- or aversion-motivated behavior.
Emily D. Prévost, Lucy A Ward, Daniel Alas et al.· Science Signaling· 0 citations
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