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Review Open access Sep 2026

Trends in the sex ratio of cannabis use, harms and perceptions among youth in Ontario, Canada, 1999 to 2023.

BACKGROUND AND AIMS Cannabis use has historically been more prevalent among men and boys compared with women and girls, yet growing evidence has suggested a recent narrowing of the sex/gender gap. Our goal was to examine changes in the sex gap in cannabis use, harms and perceptions in Ontario, Canada. DESIGN, SETTING...

Justin Matheson, A. Boak, Huan Jiang et al. · 0 citations
Open access Sep 2026

Sex and APOE Genotype Differentially Shape Microglial Transcriptomic Profiles Across the Hippocampus and Cortex

Female sex and the APOEε4 allele are top risk factors for Alzheimer’s disease (AD). Microglia play a role in the pathogenesis of AD, yet how sex and APOE genotype affect microglia remain poorly understood. Here, we characterized the transcriptomic and morphological profiles in the hippocampus and cortex of microglia fr...

S. Ledesma-Corvi, S. Blankers, Andrew J. McGovern et al. · 0 citations

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