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Author

L. Gaspar

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2 papers indexed here

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Sep 2026

Circadian Rhythms in a Petri Dish: Synchronizing Mouse Hypothalamic mHypoE-42 Cells for Circadian Clock Gene Expression Analysis.

Circadian rhythms are endogenous oscillations of approximately 24 h that regulate a wide range of cellular and physiological processes, including gene expression, metabolism, and behavior. These rhythms arise from interconnected transcriptional-translational feedback loops that respond to temporal and environmental cue...

Bárbara Ramalho, C. Fernandes, B. Santos et al. · 0 citations
Review Open access Aug 2026

A systematic review of genetic variations and DNA methylation alterations underlying circadian rhythm sleep-wake disorders.

Circadian rhythm sleep-wake disorders (CRSWDs) arise from alterations in the circadian timing system or from misalignments between endogenous circadian rhythms and environmental or behavioral demands, leading to sleep disturbances and impaired functioning. Diagnosis remains challenging and largely reliant on subjective...

Carina N. Barros, Rose Angelic Mayer, D. Garcia-Borreguero et al. · 0 citations

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