Smart Adhesive Hydrogel Delivery of Apigenin Attenuates Inflammation and Oxidative Stress in Chronic Wounds
Healing failure in chronic wounds reflects a self-reinforcing pathology of unresolved inflammation, oxidative damage, poor angiogenesis, and disordered matrix turnover, compounded by a wound bed that turns abnormally alkaline. Apigenin, a plant-derived flavonoid, counters several of these processes through antioxidant...