Open access
Aug 2026
Discovery of uracil-based antagonists and fluorescent ligands of the P2Y2 receptor.
Through a fragment recombination approach utilizing P2Y2R privileged fragments to explore non-additive SAR trends in combination with molecular docking studies, a series of potent uracil-based P2Y2R antagonists are discovered, such as compound 26a.
Mahesh Puthanveedu, Natasha C. Dale, Rebecca Knight et al.
· European journal of medicina... · 0 citations