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Open access Aug 2026

Tumor-adjacent B cell infiltration stratifies recurrence risk in localized prostate cancer

Background: Biochemical recurrence (BCR) occurs in 20-40% of men after radical prostatectomy. Existing postoperative recurrence risk tools based on PSA and pathology are clinically useful but show only moderate and variable discrimination, highlighting the need for biomarkers that improve risk stratification and conseq...

B. Wang, S. Mukherjee, A. Baj et al. · 0 citations
Open access Sep 2026

Long-Read Haplotype Phasing Resolves Allelic Configuration as a Missing Layer of Precision Oncology.

Short-read sequencing cannot determine whether co-occurring variants within a cancer gene lie on the same allele (cis) or opposing alleles (trans), a distinction with direct therapeutic consequences: trans configurations confirm biallelic tumor suppressor inactivation, whereas cis configurations generate compound oncog...

Josh N. Vo, Yi-Mi Wu, Rui Wang et al. · 0 citations

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