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Author

Lídia M. Lima

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3 papers indexed here

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Review Open access Oct 2026

Recent advances of GPR40 agonists as potential anti-Alzheimer's agents.

Alzheimer's disease (AD) is a progressive and multifactorial neurodegenerative disorder involving metabolic dysfunction, neuroinflammation, mitochondrial impairment, synaptic failure, and neuronal loss. Although amyloid-beta deposition and neurofibrillary tangles composed of hyperphosphorylated tau remain central patho...

Jefferson Muniz Alves da Silva, A. Kümmerle, D. A. Rodrigues et al. · 0 citations
Open access Sep 2026

LASSBio-753 as a new prototype of anti-tumor necrosis factor-alpha anti-inflammatory drug.

It is demonstrated that LASSBio-753 possesses significant anti-inflammatory and antinociceptive potential and may be a promising candidate for the treatment of inflammatory diseases; however, studies in inflammatory disease models are needed to better elucidate its therapeutic potential.

Tino Marcos Lino da Silva, Viviane Pinheiro Alves de Almeida, A. D. de Sousa et al. · 0 citations
Aug 2026

Preclinical characterization of the efficacy and safety of histamine H3 receptor antagonist, LINS01022, as a novel analgesic for chronic neuropathic pain treatment.

This research provides the first evaluation of LINS01022's analgesic efficacy and its favourable safety profile in neuropathic pain, and suggests that a novel H3R antagonist is a promising drug candidate and a valuable pharmacological tool for further investigation.

Magdalena Maciuszek, M. Białoń, Mateusz Królewski et al. · 0 citations

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