Sex differences in alcohol and amphetamine-like compound consumption and their relationship with mu opioid receptor density in the pallidal-mesolimbic system.
Excessive alcohol (ETOH) consumption is associated with alterations in the opioid system, including β-endorphin deficiency and differential expression of the mu opioid receptor (MOR) in brain areas involved in reward. This system also contributes to the rewarding properties of psychostimulants, such as cocaine and amph...