Open access
Sep 2026
In vivo effect of anti-PD-1 on HIV-specific CD8+T-cells in men with HIV
It is shown that a single dose of anti-PD1 increases HIV-specific CD8 + T cells in some but not all participants, and an inverse relationship between an increase in cell associated viral RNA following anti-PD1 and the percentage of specific T-cell clusters prior to administration of anti-PD-1 is demonstrated.
Céline Gubser, Lakshmi Rajdev, Chris Y. Chiu et al.
· Nature Communications · 0 citations