Author

L. Martin-Gutierrez

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Open access Sep 2026

Treatment-driven peripheral blood transcriptomic remodelling and baseline predictors of ESSDAI and STAR response to B-cell therapy in Sjögren's disease.

OBJECTIVE To characterise whole-blood transcriptomic profiles in adults with active Sjögren's disease (SjD) treated with anti-CD20 or BlyS/BAFF inhibition, identify markers of clinical response, and define inflammatory pathways linked to non-response. METHODS Whole-blood RNA sequencing was performed at baseline and w...

A. Ibrahim, Jun-Jie Peng, Eileen Tian et al. · Arthritis & Rheumatology · 0 citations

Open access Sep 2026

Monomeric CRP is prevalent in the blood of patients with rheumatoid arthritis and correlates with clinically relevant markers

Elevated C-reactive protein (CRP) is a hallmark of rheumatoid arthritis (RA) flares. CRP exists as pentameric (pCRP) and monomeric (mCRP) isoforms with distinct functions, with pCRP generally pro-inflammatory and mCRP more immunomodulatory. Standard clinical assays do not distinguish between these forms, and it rem...

Alexia Correia Ferreira, L. Martin-Gutierrez, C. Lalaurie et al. · Frontiers in Immunology · 0 citations