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Open access Sep 2026

PEOT/PBT - βTCP composites containing zinc, zinc and copper, and zinc and cobalt induce extracellular matrix deposition upon intramuscular implantation in a mini-pig model.

Bone healing is often compromised by comorbidities, limiting treatment success as can also be seen in the elderly. Current treatments, including autologous and allogeneic bone grafts, are associated with drawbacks. Synthetic biomaterials, particularly calcium phosphate (CaP) ceramics, show promise due to their chemical...

M. Nikody, Jia-Ping Li, David C. Koper et al. · 0 citations
Open access Aug 2026

Vascularization of Human iPSC‐Derived Kidney Organoids Using Perfusion Culture, Pre‐Vascularized Collagen Scaffolds, and Decellularized Extracellular Matrix

Exposure to the calcineurin inhibitor tacrolimus revealed dose‐dependent cytotoxicity and characteristic nephron and vascular injury, demonstrating the model's utility for nephrotoxicity screening and establishing foundations for physiologically relevant models for disease modeling and pre‐clinical drug testing.

Helen Kearney, Andrea Mazzoleni, Ivan Martin et al. · 0 citations

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