Review
Open access
Sep 2026
Pharmacologic Management of Pain in Children: Balancing Evidence, Safety, and Clinical Challenges
Highlights What are the main findings? Pediatric pain pharmacotherapy requires a mechanism-based and developmentally informed approach. Evidence is strongest for acute nociceptive pain, whereas treatment of neuropathic and particularly nociplastic pain remains limited by scarce pediatric-specific trials and frequent of...
Gianmarco Marcianò, A. Leo, M. Caroleo et al.
· Children · 0 citations