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Author

L. Niswander

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Open access Sep 2026

MeCP2 MBD-ID module: a unified DNA/RNA binding interface disrupted in Rett syndrome

Abstract Rett syndrome neurodevelopmental disorder is caused by mutations in the epigenetic regulator MeCP2. While the MeCP2 methyl-CpG binding domain (MBD) is well-characterized, the function of the adjacent intervening domain (ID) remains largely understudied. The ID has been described as a distinct RNA-binding regio...

J. Peter, T. Weiser, L. Niswander et al. · 0 citations
Open access Aug 2026

Faf2 is required for neural differentiation in embryonic neural progenitor cells

It is shown that knocking out Faf2 in neural progenitor cells results in increased ER stress signature at the protein and transcription level, indicating a conserved functional role in neural progenitor cells.

A. Kakebeen, Leo F. Dunphy, Heather K. Hazen et al. · 0 citations

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