Author

L. Ohno-Machado

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Open access Aug 2026

Who seeks care, and what gets measured? Understanding the distinct mechanisms behind visit and observation processes in multi-center electronic health records

Electronic health record (EHR)-linked cohorts support association, prediction, and causal studies using longitudinally measured markers of health. However, a lab biomarker measurement is recorded only when a patient first has a medical encounter (visit process) and, a clinician orders the corresponding test and the pat...

C.-H. Yang, M. Salvatore, H. Lu et al. · medRxiv · 0 citations

Preprint Jul 2026

A safety-oriented hypothetico-deductive framework for AI-assisted differential diagnosis

The findings suggest that engineering diagnostic AI as a safety-oriented reasoning framework, rather than optimizing raw predictive accuracy alone, can provide a safer, more transparent, and clinically meaningful layer of bedside decision support for acute care workflows.

F. Ma, Mauro Giuffrè, D. Wright et al. · 0 citations