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L. Onder

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Oct 2026

Evasive encounters: Immunomodulatory CAFs interact with Tregs in the lung cancer microenvironment.

Ringham et al.1 identify CHL1+CXCL9+ cancer-associated fibroblasts at lung tumor margins that recruit suppressive CXCR3+ regulatory T cells, revealing how stromal chemokine gradients can promote immune evasion. Viewed alongside immune-stimulatory CCL19+ fibroblastic reticular cells, these findings suggest that immune-i...

L. Onder, Hung-Wei Cheng, B. Ludewig · 0 citations

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