Author

L. Parrillo

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Review Open access Sep 2026

Adipose Tissue Expandability as a Link Between Nutrition and Obesity-Related Metabolic Risk: Insights from Bariatric Surgery

Adipose tissue expandability refers to the capacity of white adipose tissue to store excess energy safely while preserving metabolic homeostasis. This adaptive response takes place via both an increase in adipocyte number (hyperplasia) and size (hypertrophy). Healthy expansion requires coordinated angiogenesis, extrace...

Emilia Jiménez-Flores, C. Reytor-González, Dolores Jima Gavilanes et al. · Nutrients · 0 citations

Open access Sep 2026

Adipose tissue dysfunction in obesity and type 2 diabetes: the role of DNA methylation linking adipogenesis to metabolic disease

Adipose tissue plasticity, sustained by the recruitment and differentiation of adipocyte precursor cells (APCs), is a key determinant of metabolic health. Failure of this adaptive program, rather than fat mass per se, represents an early contributing factor in the progression toward insulin resistance (IR) and type 2...

F. Zatterale, Rosy D'Agostino, P. Florese et al. · Cell & Bioscience · 0 citations

Open access Jul 2026

Blood-Based DNA Methylation Models Improve Short-term Cardiovascular Risk Stratification in Individuals With Type 2 Diabetes

The DNAm-based models generated may improve risk stratification for short-term cardiovascular events in individuals with T2DM, providing a promising approach to refine identification of those at increased risk of MACE.

M. Longo, Antonella Desiderio, M. Masulli et al. · Diabetes Care · 0 citations