Pathogenesis, clinical and histological features of calcineurin inhibitors induced nephrotoxicity: Literature review
Since the 1980s, calcineurin inhibitors (CNI) have been widely used as immunosuppressive agents in solid organ transplantation and in the treatment of immune-mediated glomerular diseases, including complicated nephrotic syndrome. However, CNI-induced nephrotoxicity (CNIT) remains one of the most frequent adverse effect...