L. S. Machado

Evaluating the accuracy of brief cognitive assessments for the early detection of cognitive impairment in adults across primary and specialty care settings: A systematic review and meta-analysis.

BACKGROUND This systematic review and meta-analysis aimed to assess the accuracy of brief (i.e., ≤15 minutes), freely available cognitive tests for the early detection of cognitive impairment (including mild cognitive impairment and dementia) in adults 55 years and older in primary and specialty care. METHODS A syste...

Metabolic brain network reorganization precedes clinical conversion in Alzheimer’s disease

Differential associations of tau extent and load with brain metabolic and cognitive dysfunction in Alzheimer's disease

Across regions and networks, SEOT performed similarly or better than tau load in predicting metabolic dysfunction and may improve diagnostic characterisation and prediction of cognitive impairment beyond [18F]FDG-PET.