Open access
Aug 2026
Beyond the full-length toxin: The metalloprotease domain of Pictolysin-III retains key functional properties and cellular activity.
Snake venom metalloproteinases are major determinants of viperid venom pathology, but the specific contribution of their metalloprotease domain to toxin function remains insufficiently defined. Here, we produced and characterized the metalloprotease domain of Pictolysin-III, a P-III metalloproteinase from Bothrops pict...
A. Roque, D. Torrejón, Alex Proleón et al.
· Biomedicine & pharmacotherap... · 0 citations