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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

Author

L. Sacchi

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Open access Sep 2026

Exploring the interplay between frailty, Alzheimer's disease biomarkers, and cognitive functioning in patients with mild cognitive impairment: A cross-sectional study

Background Frailty is characterized by declining homeostatic reserves and increased vulnerability to stressors, and has been associated with cognitive decline and dementia. Objective To examine the relationship between frailty, Alzheimer's disease (AD) biomarkers, and cognitive performance in individuals with mild cogn...

Manuela Pintus, M. Valletta, L. Sacchi et al. · 0 citations
Nov 2025

DTI‐ALPS Primarily Reflects White Matter Diffusion Dispersion and Microstructural Heterogeneity in Neurodegeneration: Insights From Multi‐Modal MRI

Factor analysis indicated that DTI-ALPS clustered with MA and ODI rather than forming a distinct factor, suggesting that DTI-ALPS primarily reflects WM diffusion dispersion and heterogeneity rather than glymphatic flow in the context of neurodegeneration.

L. Sacchi, Giovanni Farruggio, Giorgio Bocca et al. · 1 citation
#diffusion models Open access Sep 2026

Assessing glymphatic role in the association between choroid plexus enlargement and white matter lesions load: The uncertain path through diffusion tensor imaging along the perivascular space (DTI-ALPS).

CP enlargement is associated with reduced DTI-ALPS and greater WML burden, but the contribution of glymphatic impairment remains uncertain, and alternative mechanisms may contribute to these findings.

L. Sacchi, Valentina Veronesi, Giorgio Bocca et al. · 0 citations
Open access Sep 2026

Microglia-derived extracellular vesicles uncover early alterations of inflammatory signaling in Alzheimer's disease.

Findings support the presence of a compartment-specific reorganization of inflammatory signalling during AD progression and highlight the potential of MDEVs as accessible peripheral biomarkers of neuroinflammatory processes in AD.

Chiara Bianchessi, M. Serpente, E. Ferri et al. · 0 citations

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