Open access
Jul 2026
LAMP2A-dependent chaperone mediated autophagy regulates Notch signaling and controls neural stem cell differentiation.
It is shown that CMA is active in NSCs, while expression of LAMP2A, the principal limiting component of CMA, is associated with the induction of neurogenesis, and it is demonstrated that LAMP2A is involved in NSC fate decisions by interfering with NOTCH1 signaling pathway.
Daphne Antoniou, M. Xilouri, D. Gkikas et al.
· Cellular and Molecular Life... · 0 citations