Author

L. Vellucci

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Open access Sep 2026

30. Brain hypometabolism and disorganization domain as putative neuronal correlates in schizophrenia: a comparative head-to-head treatment-resistant vs. treatment-responsive schizophrenia PET study

Abstract Background About a third of schizophrenia patients are refractory to antipsychotics, a condition characterized by poor clinical and functional outcomes known as treatment-resistant schizophrenia (TRS). The disorganization domain may represent the leading factor in categorizing a schizophrenia patient as affect...

M. Ciccarelli, F. Iasevoli, A. Barone et al. · International Journal of Neu... · 0 citations

Open access Sep 2026

181. Integrating clinical profiles and microRNAs to uncover molecular mechanisms in treatment-resistant schizophrenia

Findings suggest that increased expression of these miRNAs may enhance gene silencing across synaptic and intracellular signaling cascades, potentially contributing to impaired neuroplasticity and treatment resistance through downregulation of critical neurotransmission-related targets.

L. Vellucci, P. Mirra, A. Nasti et al. · International Journal of Neu... · 0 citations

Review Open access Sep 2026

Addressing fusiform gyrus dysfunction in schizophrenia, theory of mind, and implications for antipsychotics' response and resistance: A systematic review and critical appraisal.

The Fusiform Gyrus appears to function as a dynamic, state-sensitive hub underlying perceptual, emotional, and cognitive disturbances in schizophrenia, in line with impaired ToM.

M. Ciccarelli, B. Mazza, A. Nasti et al. · Neuroscience and Biobehavior... · 0 citations