Open access
Aug 2026
Synthesis of a guanylylated peptide derived from norovirus VPg as a molecular tool for studying norovirus replication
Norovirus is a leading cause of global acute gastroenteritis, yet the mechanisms underlying its replication remain incompletely understood. As a positive-sense single-stranded RNA (+ ssRNA) virus, norovirus utilizes a nucleotidylated viral protein (VPg) as a primer for synthesis of its genomic and subgenomic mRNAs. In...
Bob van Puffelen, L. X. Neves, Roy Steneker et al.
· RSC Chemical Biology · 0 citations