Correlation of high PRDX4 expression with poor prognosis in patients with ESCA: Bioinformatics and in vitro validation
Esophageal cancer (ESCA) is a highly lethal gastrointestinal malignancy with limited therapeutic options. The peroxiredoxin 4 (PRDX4) protein has antioxidant functions and is implicated in various types of cancer, but its role in ESCA remains poorly understood. The purpose of the present study was to investigate PRDX4...